Research comparison
Ipamorelin vs Sermorelin: research comparison
Ipamorelin and sermorelin are different classes of research peptides often mentioned together in growth-hormone axis literature. Ipamorelin is a selective ghrelin/GHS-R agonist pentapeptide; sermorelin is a GHRH (1–29) amide analogue. This page compares registry identities only.
Sermorelin is not a BioLabs Research catalog SKU. Ipamorelin appears on-site as part of the Tesamorelin / Ipamorelin blend listing — not as a guaranteed standalone vial. Confirm the live product page for what is actually sold.
Quick comparison
| Field | First | Second |
|---|---|---|
| CAS | 170851-70-4 | 86168-78-7 |
| Approx. formula | C38H49N9O5 | C149H246N44O42S |
| Approx. MW | ~711.9 Da | ~3357.9 Da |
| Class framing | GHS-R / ghrelin mimetic pentapeptide | GHRH (1–29) amide |
| Catalog note | In Tesamorelin/Ipamorelin blend | Not listed |
Ipamorelin
Ipamorelin (CAS 170851-70-4) is a short peptide research tool with sequence motif Aib-His-D-2Nal-D-Phe-Lys-NH2 in public descriptions. Molecular weight is far lower than GHRH analogues. On this site, see the blend identity article and product: Tesamorelin / Ipamorelin identity, blend product.
Sermorelin
Sermorelin (CAS 86168-78-7) corresponds to GHRH (1–29) amide in public chemistry records (large peptide, multi-kilodalton range). It is not interchangeable with ipamorelin, CJC constructs, or tesamorelin. Because it is not catalogued here, use PubChem and your supplier COA for identity confirmation.
Do not assume that a GHRH analogue blend on the shelf contains sermorelin unless the COA sequence says so.
Key differences
- Orders-of-magnitude difference in molecular weight.
- Different receptor-class framing (GHS-R mimetic vs GHRH fragment).
- Distinct CAS numbers; not salt forms of one another.
- Only ipamorelin-related material appears on-catalog (blend).
Which for which research context
Ipamorelin-focused work — confirm whether you need the standalone identity or the tesamorelin/ipamorelin blend actually offered.
Sermorelin-focused work — source from a supplier that prints CAS 86168-78-7 / GHRH(1–29) on the COA; not available as a BioLabs SKU.
References
- Ipamorelin: PubChem CID 9831659 · CAS 170851-70-4
- Sermorelin: PubChem CID 16129620 · CAS 86168-78-7
All discussion on this page is limited to chemical identity, public registry identifiers, and laboratory research framing. BioLabs Research lists reagents for in-vitro and analytical work only. Confirm vial strengths and any hosted COA PDFs on the product page or in the COA Library.
Use the solution dilution calculator and unit converter for lab math only. Related reading: blog, Science, reading a COA, Shipping.
When protocols mention “GHRP” versus “GHRH”, map the acronym to the actual sequence before ordering. Mis-picking a pentapeptide for a 29-mer (or the reverse) wastes budget and invalidates concentration assumptions.
For dilution of lyophilized vials once identity is confirmed, use mg and mL only in the dilution tool.
For laboratory research use only. Not for human or veterinary use. No medical claims; no human dosing guidance.